Nabsys uses proprietary electronic nano-channel detectors to analyze long DNA molecules at high velocity. Electronic detection enables Nabsys to achieve significantly higher resolution than can be obtained using optical mapping methods. Nabsys HD-Mapping™ solid-state electronic nano-channel detectors build whole genome maps with sub-diffraction-limit resolution that are truly high definition. These maps offer compelling advantages for the analysis of structural variation, the assembly of genomes, and as a method for confirming putative variants called using other technologies.HD-Mapping works by adding sequence-specific tags to long DNA molecules. These molecules pass through the nano-detectors at high velocity using a combination of electrophoretic and hydrodynamic control. The detectors report the locations of the sequence-specific tags on the molecules. The information is then analyzed by Nabsys analytical software. Key application areas that are enabled by Nabsys include:• De Novo Assembly• Structural Variant Discovery• Variant Verification• Microbiome Analysis• Metagenome Characterization• Hybrid AssemblyNabsys provides the complete solution for electronic genome mapping. The Nabsys HD-Mapping platform includes:• HD-Mapping instrument • Electronic nano-channel detector chips • Complete run reagent cartridge • Sample prep kit• Comprehensive control and data analysis software Nabsys HD Mapping provides routine, accurate, cost-effective analysis of genomic structural information. The HD-Mapping platform employs fully electronic detection of tagged single DNA molecules to provide significantly higher sensitivity, accuracy, scalability and speed of detection in comparison to existing mapping technologies. Single-molecule reads, hundreds of kilobases in length, have high resolution and low error rates, resulting in high information content per read.

DNA Sequencing Nanopore Solid-state nanodetectors Electronic detection Biochemistry Genome mapping Genome Assembly Structural Variation Strain Identification De Novo Assembly Assembly Scaffolding Metagenomics Microbiome Pathogen Identification SV Validation SV Discovery B2B Biotech SaaS Commercial Physical Research Biotechnology