Biotechnology - Mumbai, Maharashtra, India
We perform classification and recognition of complex liquids in the same way as humans do which is very untypical type of analysis for conventional analytical chemistry and traditional analytical techniques. Taste Masking, Benchmarking or Reference Matching.....Taste, Flavours or odors are so entwined in our experience that most people are unaware that most of what they call taste is really an olfactory experience.The artificial taste assessment can be a very challenging task when the substances responsible for the taste have different chemical structure. To evaluate bitterness of NCE, we generate quantitative prediction of bitterness scores (calibration) of diverse APIs, both inorganic and organic, on the basis of a multivariate calibration based on known (Human) H Scores. Influence of the lipophilicity of the substances on the sensor response may be especially important for the measurements of bitterness intensity as hydrophobicity was reported to be correlated with bitterness intensity. Our studies involving ODTs - Oradispersible tablets demonstrates the influence of the dissolution medium on the drug release rate at different time points starting 15 seconds. Wide spectrum of host of instruments are available which have different active principles having a bias on latest developments of analytical instrumentation. These have to be evaluated and our current level of knowledge of understanding has to be broadened to disseminate the knowledge to the user industry. This serves the twin objectives, of application of state of art technology and serve the interest of consumers who are vulnerable due to subjective evaluation.
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