Research - , ,
AUTOSTEM is an EU H2020 project that is developing a closed, automated, sterile pipeline for large-scale production of therapeutic stem cells. The project will enable lower-cost, higher-quality and more consistent stem cells to be produced, ultimately helping patients worldwide to benefit from new stem cell therapies.Stem cells offer new hope as a treatment for several diseases and conditions, including arthritis, diabetic complications, liver disease and several cancers. Hundreds of clinical trials are now in progress, testing new stem cell therapies. However, current manufacturing protocols for stem cells are inefficient and labour intensive, requiring highly-skilled teams of technicians operating in a clean-room environment. As new stem cell therapies are approved and come on-stream, there is a real risk that the future supply of stem cells will not be able to meet clinical demand. AUTOSTEM will revolutionise the stem cell production process, generating clinical quantities of high quality stem cells at an affordable cost. This will enable the routine clinical use of stem cell therapies in the future.The AUTOSTEM consortium is a multi-disciplinary mix of engineers, regenerative medicine scientists and high-tech companies from 4 different European countries. The project is led by Dr Mary Murphy of the National University of Ireland, Galway. The consortium includes the following partners:NATIONAL UNIVERSITY OF IRELAND, GALWAYUNIVERSITY OF GENOAFRAUNHOFER-IPTTYNDALL- UNIVERSITY COLLEGE CORKPINTAIL LIMITEDCROSPON LIMITEDZELLWERK GMBHCELL THERAPY CATAPULT LIMITEDASTON UNIVERSITYORBSEN THERAPEUTICS LIMITEDThe AUTOSTEM project has received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement no 667932.
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