Research - Miserey, Normandy, France
BIOANALYSIS and BIOPHARMACY- pKa, LogP, LogD, Physiological solubility and stability- in-vitro, in-vivo and ex-vivo assay studies.- Permeability, Absorption, Distribution.- BCS determination.- Franz Cells , Ussing chambers (Skin, Buccal and Nasal mucosa, intestinal segments, corneal and scleral permeability).- Eye distribution and Pharmacokinetic.- In-vitro / in-vivo correlation.ANALYTICAL SERVICES- HPLC-MS-MS ,DAD, UV.- GCMS-EI.- Spectrometry (fluorescence and luminescence), Elisa.COSMETIC SERVICES- Chromatographic qualification and quantification of preservatives (ISO 9001, ISO 22716). - UV filters and vitamin (ISO 9001, ISO 22716).- Actives ingredients analysis.- In-vitro testing : Cutaneous absorption in Franz cells according to guideline OCDE 428. Skin and ocular irritation test. Phototoxicity test. Microbial adhesion on human skin and mucosal segments.