Pharmaceuticals - Union City, California, United States
Catylix was founded by Professor John Hartwig, Dr. David Rozzell, and Dr. Brian Adger to develop better methods for producing biologically-active compounds with improved pharmacokinetic properties. One of the most effective ways to improve the pharmacokinetic properties of a bioactive compound is the introduction of a fluorine-containing functional group. Fluorinated substituents have been shown to improve lipid solubility, receptor binding, metabolic stability, and bioavailability, which can dramatically improve the performance of a potential drug.The company's first product, trade-named Trifluoromethylator, is a new, shelf-stable reagent allowing the derivatization of a broad range of compounds with a CF3 group under mild conditions. Catylix is expanding the chemistries it practices to include additional chemical functionality that to improve the properties of compounds targeted for the pharmaceutical and crop protection markets. Services for the preparation of trifluoromethyl-substituted aryl and heterocyclic compounds on a custom basis will also be available.Catylix's goal is to provide the first-in-class methods and supporting services for broadening the scope of compounds available for medicinal, veterinary, agrochemical, and advanced materials applications.
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