Research - Huningue, Alsace, France
Within Basel neighbourhood and at the very heart of Europe (the triple border of France, Germany and Switzerland), Firalis is a pioneering biotechnology company, active in discovery, development and qualification of biomarkers (BM).1) BIOMARKER PRODUCTSFiralis develops BM-based diagnostic, prognostic and theranostic tools:● RUO Kits (Research-Use-Only), based on validated innovative biomarkers● IVD Tools (In Vitro Diagnostic), based on a combination of clinically qualified biomarkers2) BIOMARKER R&D● Development of proprietary BMs - Cardiovascular, Inflammatory, Autoimmune and Neurology● Drug Safety & Drug Efficacy● Patient Stratification● Personalized Medicine3) BIOMARKER-RELATED CRO SERVICESBM Discovery for laboratories, biotechs and pharmaceutical industry:- Proteomics: Soluble biomarker measurements with several immunoassays technologies (ELISA, multiplex and high sensitivity platforms such as Luminex® BioPlex 200™, Meso Scale Discovery®, Singulex Erenna®, Protein Simple Ella™, Olink and Siemens Dimension® EXL™ 200)- Genomics/Transcriptomics: Targeted sequencing of miRNA and mRNA (HTG EdgeSeq), lncRNA screening via Firalis proprietary platform, Next-Generation Sequencing (NGS) services (RNA-Seq, whole genome and exome sequencing, etc.) and qPCR/microfluidic qPCR (Gene Expression, SNP, CNV, etc.)- Flow Cytometry: Immunophenotyping of preclinical and clinical samples, monitoring of pharmacodynamics on target cells in response to treatment and biomarker discovery- Assay development and validation on various platforms, development of critical reagents (antibodies and proteins)- Biobanking and sample repository services supported by LIMS- Data analysis using multi-parametric statistics and development of predictive models- Support of regulatory activities related to biomarker qualification with Health Authorities (FDA/EMA)- Quality environment (ISO 9001, ISO 13485 (GMP), ISO 17025 (GLP/GCLP))For more information please visit our website.
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