Biotechnology - Worcester, Massachusetts, United States
Cardiovascular Physiology and Surgical Rodent CoreThe UMASS Cardiovascular and Surgical Rodent Core is a leader in the field of cardiovascular translational research. We investigate molecular and cellular events that are vital for the regulation of normal and pathological cardiovascular function. The core conducts studies that utilize new and "gold standard" mouse models of cardiovascular disease. We collaborate with investigators to design various specialized surgical and physiological studies involving transgenic, knockout, or other mouse models that manifest cardiovascular phenotypes.Our continuously growing development and availability of well-defined genetic strains, provide us with the ability to create transgenic and knockout mice, Making these mouse models extremely valuable biomedical research tools. Paired with our ability to manipulate these mice surgically is key for cardiovascular research with the mouse models. We provide investigators with an easily accessed resources for creating and development of mouse cardiovascular disease models. Providing unique and valuable research tools for translational research from animal studies into human applications. The Mouse Cardiovascular Core develops timely and cost-effective solutions to important functional aspects of mouse models with respect to clinical applications.Our core is proud to offer a wide variety of non-invasive and surgical procedures for comprehensive evaluation of cardiovascular phenotypes for transgenic and knockout mice. Using mouse models of cardiovascular disease and heart failure requires hiring personnel with advanced microsurgical skills and expensive instrumentation. We offer these services that are difficult and time-consuming for you without proper expertise, experience and equipment. We provide you with the ability to efficiently find necessary information about various animal models, in-depth solutions for comprehensive assessment of cardiovascular function in mice, and