INFINITE - Lille Institute for Translational Research in Inflammation
Research - Lille, Nord-Pas-de-Calais, France
INFINITE - Lille Institute for Translational Research in Inflammation Employees
INFINITE - Lille Institute for Translational Research in Inflammation Details
INFINITE is a unified institute devoted to the study of inflammation, from its origins to its consequences. We use digestive and systemic inflammatory diseases as models to assess the origin of inflammation, its pathophysiology, and its consequences (fibrosis and impaired regeneration). We are developing new drugs, therapeutic strategies, and biomarkers. Each model and each project will benefit from INFINITE's complementary, cross-disciplinary skills (complementary medical and scientific skills) to characterize the causes and consequences of chronic inflammation. The close relationship between INFINITE and the FHU/clinical departments ensure that scientists have access to biological resource centers and well-defined cohorts of patients with chronic inflammatory diseases. This enables high-level translational research, which is INFINITE's hallmark. Our program is built on scientific questions organized into four interconnected WPs exploring the origins of inflammation (environment, microbes) (WP1), the mechanisms of chronic inflammation, impaired regeneration (WP2), fibrosis (WP3), and innovative therapeutic and diagnostic approaches (WP4). The WPs are strongly inter-connected with interactions between environmental factors/microbes, epithelial cells, the mucosal barrier and the immune system, leading to the development of innovative treatments and diagnostic tools.
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