Klotho Therapeutics, Inc.
Research - San Diego, California, United States
Klotho Therapeutics, Inc. Employees
Klotho Therapeutics, Inc. Details
Helping people live well longerKlotho Therapeutics, Inc., (KTI) is a privately held biotechnology company developing modified recombinant versions of the human protein Klotho that has shown great potential to delay diseases of aging and improve longevity. The company builds upon the $100+ million invested in Klotho related academic research that demonstrates how Klotho, a naturally occurring protein in humans and animals, can positively impact aging, cognition, kidney function, fibrosis, and cancer. KTI has worldwide patents pending on modified, recombinant Klotho proteins that can be readily manufactured using standard cell culture technology.De-risking development accelerates human trialsKTI is minimizing the standard risks of an early stage biotech by de-risking each component of the development process. Its capital efficient structure will reduce the cost and time of getting to human trials. KTI is well positioned to enter human trials within 12-15 months focused on its first indication: to slow the progression of kidney failure, which affects up to 40 million patients in the US per year, with over 600,000 currently on dialysis. Kidney disease represents a multi-billion dollar market opportunity in the U.S. alone. Virtual team of world-leading expertsKTI is led by founder James "Jim" Plante, a serial healthcare and technology entrepreneur and experienced biotech investor, who has achieved several successful financial exits. KTI's virtual management team is comprised of seasoned executives, including:• Jim Plante − Founder, Chairman & CEO• Dinesh Raturi, MD − VP, Director Operations• William Ramage, DPhil − Chief Development Officer• Joseph Tarsio, PhD, MBA − R&D• Debra Richardson, PhD – PatentsThe company is also well supported by the world's leading Klotho experts on its Medical Advisory Board including the discoverer of Klotho protein and gene, clinical researchers and a specialist in ICU acute kidney injury.
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