Research - Leiden, South Holland, Netherlands
Sells automated microinjection systems used for two applications: 1) Automated zebrafish injections Using a special grid, zebrafish eggs are aligned such that microinjection can take place at an unprecedented speed of 2500 eggs per hour. The discovery of the possibility to infect and monitor tuberculosis progression in zebrafish is described in PLoS ONE, 2010. http://dx.plos.org/10.1371/journal.pone.0016779 2) Automated 3D tissue culture Mixing polymers with a cell suspension allows for instant cell tissue creation at predefined locations in a hydrogel. The use of these injected cell spheroids in high-throughput quantitative cancer invasion screens is described in Biomaterials, 2012. http://dx.doi.org/10.1016/j.biomaterials.2011.09.049 Development of zebrafish culture platform and late stage embryo injection system. Development of next-gen sequencing software tools.
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