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The Ontario SPOR SUPPORT Unit (OSSU) is a collaborative network across 12 leading Ontario health research centres. Jointly funded by the Government of Ontario and the Canadian Institutes of Health Research, the initiative engages researchers, patients, clinicians, policy makers, industry representatives and other health system professionals to implement Canada's Strategy for Patient-Oriented Research within Ontario. In particular, OSSU provides infrastructure, expertise and support to those engaged in patient-oriented research, and promotes knowledge transfer and exchange of the latest research evidence to inform and implement more effective health policy and clinical practices throughout the province.