Biotechnology - Toronto, Ontario, Canada
Phoenox Pharma is an early stage biotech company focusing on delivering mitochondrial inhibitors specifically to cancer stem cells for the treatment of orphan oncology indications of significant unmet need. Cancer is the leading cause of death in Canada and is responsible for 30% of all deaths. Cancer stem cells (CSCs) are a phenomenon common to all malignancies and drive recurrent disease, metastasis and ultimately death of the cancer patients. While an attractive target, anti-CSC therapeutic agents are not yet on the market and have been limited by toxicity in clinical trials. To accelerate development, Phoenox is designing a suite of polypharmacologic prodrug molecules in partnership with Cyclica, an artificial intelligence drug development firm.