Medical Practice - , British Columbia, Canada
Repeat Diagnostics was set up as a spin-off from the British Columbia Cancer Agency (BCCA), when requests for telomere length measurements using the flow FISH technique overwhelmed the research laboratory of Dr. Peter Lansdorp, where this technique was developed and perfected.The Flow FISH technique is highly reproducible and accurate and more informative compared with other methods such as Southern Blot analysis of restriction fragments and PCR based techniques. Repeat Diagnostics offers telomere length profiles in relationship to age-matched controls. This more informative technique allows analysis and comparisons of the telomere length between different cell types and within one cell type, e.g. in longitudinal studies. Such studies have shown that the telomere length declines with age, and following transplantation follows distinct patterns in T cells, B cells and hematopoietic precursor cells.
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