Ripple Biosolutions
Research - Seattle, Washington, United States
Ripple Biosolutions Employees
Ripple Biosolutions Details
We firmly believe in the promise of next-generation DNA sequencing (NGS) as an effective and ubiquitous clinical tool for molecular surveillance of a person's health. In addition, collective wisdom from patients, doctors, and researchers informs us that the most durable cures for cancer occur when the disease is detected and treated early in its progression. Ripple Biosolutions addresses the technical challenges inherent in creating unequivocal tests for early detection and sensitive monitoring of tumors using the non-invasive technology of "liquid biopsy".Current NGS-based liquid biopsies have a reliable (>95%) accuracy threshold when circulating tumor DNA levels exceed 1% of total circulating DNA. To enable the goal of early cancer detection, we set the aggressive requirement that the Ripple Biosolutions test be an order-of-magnitude more sensitive than current technologies, while maintaining the clinical requirement for >95% accuracy. We refer to this initiative as "The 0.1% Solution."Our research approach has yielded novel innovations that meet the 0.1% Solution objective. Ripple Biosolutions technology reliably detects circulating tumor fragments present at 0.1% of total circulating DNA. Moreover, we have created a scalable proficiency testing infrastructure that can be applied across clinical laboratories to document and validate test performance.In collaboration with PlasmaLab International (plasmalab.com) we have recently launched a purified, high-performing, circulating cell-free DNA (cfDNA). Each lot of UltraPure cfDNA is produced from a single healthy human donor. This is an assay-ready, highly robust product that meets or exceeds performance of cfDNA purified by the current "gold standard" method. Please refer to the "Products" page on our website for further details.
Ripple Biosolutions Technologies
E-commerce Platforms
Squarespace ECommerce
Email Providers
Outlook
Fonts
Typekit
Other
Mobile Friendly