Major Drugs - Cambridge, MA, US
President, CEO, Chief Science Officer (CSO), Founder, Director (Biologist and Pharmacologist)
President, CEO, Chief Science Officer (CSO), Founder, Director (Biologist and Pharmacologist)
Privately held central nervous system (CNS)-focused therapeutics company founded in March 2013 by biologist and pharmacologist James P. Pearson PhD (JPP) and medicinal chemist/ process chemist Eduardo J. Martinez PhD based in Cambridge MA, USA. Sea is working on discovery, research, development (R&D) and commercialization of novel proprietary synthetic small molecules as innovative treatment of the devastating neurological disease Sporadic ALS (Amyotrophic Lateral Sclerosis) and other CNS indications. Sea works with a network of Key Opinion Leaders in neuroscience, pharmacology and chemistry. Sea's consultant neurologist/ neuropathologist is ALS expert Shin Kwak MD, PhD (Tokyo Medical University). Dr. Kwak was prof. 30 years at University Tokyo. Dr. Kwak discovered (human data) a key editing defect specific to sporadic ALS patients' glutamate receptors/ ion channels (not found in familial ALS patients). This leads to death of motor neurons in sporadic ALS. Sea is a State of Iowa Limited Liability Company. Sea has 8 board members (i) JPP, Sea president, CEO and chief scientist (ii) Ben Cravatt PhD neurochemist /biologist Professor TRSI (Scripps), member National Academy of Sciences; ActivX ( Kyorin), Abide (Lundbeck), Vividion; (iii) Eric R Olson PhD biologist and pharmacologist CSO Syros Inc Cambridge MA, board member Cystic Fibrosis Foundation; drug maker 3 life-saving CF drugs Kalydeco_TM, Orkambi_TM, Symdeco_TM frmr Aurora Biosciences INC / Vertex, Parke-Davis, Upjohn;(iv) Mark G. Currie PhD (frmr CSO Cyclerion, Ironwood; frmr Sepracor, Monsanto); drug maker Celebrex_TM, Bextra_TM, Lunesta_TM, Xopenex_TM, and Linzess_TM ;(v) Michael J Higgins MBA (frmr Ironwood Pharma, Genzyme, Procept); (vi) Shaker Sadasivam PhD frmr CEO Sun Edison Semi Conductor (SEMI sold in 2016), Monsanto; (vii) Nabil Elkouh PhD, Erigo LLC and expert metals and battery engineer; (viii) W. Kendall Brown JD physicist and lawyer.
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