Stop Parkinson's Disease
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Stop Parkinson's Disease Details
Parkinson's is a devastating disease that has no cure. Current medicines only treat symptoms temporarily, though most patients are not informed of that sad fact. While physicians are prescribing drugs for the symptoms, the degeneration continues, the neurons and other cells in the brain continue to die, until disability becomes profound and mortality rates increase.\\Yet there are literally hundreds of research papers demonstrating that a number of substances, mostly phytochemicals, are neuroprotective in Parkinson's models. These models include cell culture and animals, but not humans. Phytochemicals are not synthetic drugs, they come from plants so there's no money to be made by the drug companies. The result is that research on these substances almost never includes human clinical trials.\\But Parkinson's sufferers don't have the 50 years or so necessary to do human trials on some of these substances. They need options today, even if those options are long shots. Why are they long shots? Well there are many reasons these substances wouldn't work on humans, including bioavailability, the blood-brain barrier, inadequacies of the models, etc.\\So what do we do? We create algorithms to search the medical literature to find hidden patterns suggesting which substances are most promising. Then we add those substances together in a kind of Hail Mary pass, and give patients the option, the possibility to stop their disease, rather than just treating symptoms.
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