Pharmaceuticals - Philadelphia, Pennsylvania, United States
Telesis Therapeutics is an early stage biopharmaceutical company. The mission is to accelerate breakthrough discoveries from research institutions into therapies for patients. We are advancing a portfolio of discoveries through effective collaborations with institution partners, disease foundations, and pharma industry partners. Our development and commercial focus is oncology, and includes small molecules, antibodies, proteins, and nucleotides. In oncology Telesis Therapeutics will identify, develop, and de-risk licensed discoveries, that have issued or pending patents and positive early preclinical data. Our business model includes early stage discovery research, drug synthesis, IND enabling/safety studies, and clinical development through to Ph III trials and FDA approvals, with associated milestones. Telesis Therapeutics will commercialize assets at the earliest stages of development. We are actively building relationships with potential licensing and industry development partners.Telesis Therapeutics has acquired TTL-315, a patented discovery. This potential cancer therapy is a small molecule, anti-metabolite, being developed for the treatment of solid tumors. Treatment of solid tumors accounts for 70% of the global cancer market. TTL-315 has a unique mechanism of action, published positive cell and animal data, with a global intellectual property portfolio.Telesis Therapeutics lead indication for TTL-315 is for the treatment of patients with pancreatic cancer (PDAC), which represents the fourth leading cause of cancer death in the USA, and is expected to be the 2nd leading cause of cancer death in the USA by 2030. The one year survival rate for this orphan indication is 20%, and the five year survival rate is 9%. Indications to follow: Triple negative breast, colorectal, and small cell lung cancers.
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