ForBetterHealth is a moonshot program of clinical research and solution development dedicated to ending health disparities in Black, brown and underserved populations in the U.S. Our purpose is to make a meaningful impact on health outcomes for the populations we serve. We intend to accomplish this goal through the development of a commercially led ecosystem of social enterprises in health care, including public-private partnerships. Our core design principle is to optimize the application of science, technology, people and place in the creation of innovative health care services.