The CIB, in its modern facilities and with its scientific, technical and administrative personnel (85 staff scientists, around 60 postdoctoral, 165 predoctoral fellows, and 150 persons devoted to technical and administrative duties), is in a privilege situation to face all these challenges, maintaining its brilliant intellectual performance. We expect that the future Spanish and European scientific policy will allow developing all the CIB capabilities and we are certain that the CIB is prepared to do it.