Paula Kaplan-Lefko
Associate Director, Clinical Regulatory Affairs at Atara Biotherapeutics - Thousand Oaks, California, US
Paula Kaplan-Lefko's Colleagues at Atara Biotherapeutics
Preeti Ravaliya
Director, Commercial Operations, Analytics and Data Management
Paula Kaplan-Lefko's Contact Details
(805) 623-4211
Thousand Oaks, California, United States
Atara Biotherapeutics
Paula Kaplan-Lefko's Company Details
Atara Biotherapeutics Inc., is a leading allogeneic T-cell immunotherapy company pioneering the development of transformative off-the-shelf therapies for patients with serious diseases including solid tumors, hematologic cancers, and autoimmune diseases. With our lead program receiving marketing authorization in Europe, Atara is the most advanced allogeneic T-cell immunotherapy company and intends to rapidly deliver off-the-shelf treatments to patients with high unmet medical need. Our platform leverages the unique biology of EBV T cells and has the capability to treat a wide range of EBV-associated diseases, or other serious diseases through incorporation of engineered CARs (chimeric antigen receptors) or TCRs (T-cell receptors). Atara is applying this one platform, which does not require TCR or HLA gene editing, to create a robust pipeline including: tab-cel for Epstein-Barr virus positive post-transplant lymphoproliferative disease (EBV+ PTLD) and other EBV-driven diseases; ATA188, a T-cell immunotherapy targeting EBV antigens as a potential treatment for multiple sclerosis; and multiple next-generation chimeric antigen receptor T-cell (CAR-T) immunotherapies for both solid tumors and hematologic malignancies.