The mission of Institute for Myelin and Glia Exploration is to study myelin and its diseases. Basic research is based on a multi-disciplinary approach to understand how myelin is formed, how it is damaged in disease, and how it may be repaired. In particular, we study disease mechanisms of Krabbe Disease in order to formulate therapies. We strive to generate information that will promote effective treatment strategies not only for children with leukodystrophies, but also patients with Multiple Sclerosis, stroke, neuropathies and other diseases in which myelin is damaged. The Institute for Myelin and Glia Exploration is a partnership with the University at Buffalo. As a research institute of the University at Buffalo's Jacob School of Medicine & Biomedical Sciences, all research, including both clinical and basic science, is coordinated through the Institute, which is located at the New York State Center of Excellence in Bioinformatics and Life Sciences, a part of the Buffalo Niagara Medical Campus, in downtown, Buffalo, NY.