Enterome
Biotechnology - , Ile-de-France, France
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Enterome Details
We are a clinical stage biopharmaceutical company developing first-in-class immunomodulatory drugs based on our unique ability to de-code the gut microbiome's interaction with the immune system.We have developed two highly promising pipelines of clinical and pre-clinical candidates with a focus on cancer and auto-immune diseases:- OncoMimics™: highly effective, off-the-shelf therapeutic vaccines against cancers (EO2401, EO2463). EO2401 is in Phase 1/2 clinical trials in patients with glioblastoma and adrenal tumors. EO2463 is in a Phase 1/2 clinical trial for indolent non-Hodgkin B-cell lymphomas. - EndoMimics™: a pipeline of next generation bioactives acting like human hormones or cytokines for the treatment of immune diseases. EB1010, the lead candidate, is a potent local inducer of IL-10 designed to provide improved therapeutic outcomes for patients with IBD. In addition, Enterome's clinical candidate sibofimloc (also referred to as TAK-018) is advancing through a Phase 2 clinical trial in post-operative Crohn's disease. Sibofimloc has been partnered with Takeda globally, with Enterome retaining a significant profit share in the US.
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